Letter by Koh Regarding Article, “Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study)”
نویسندگان
چکیده
منابع مشابه
Canagliflozin and cardiovascular and renal events in type 2 diabetes.
Review of: Neal B, Perkovic V, Mahaffey K, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377:644-657. The report combines the data from two trials, CANVAS and CANVAS-Renal, which were designed to evaluate the safety and effect of canagliflozin, an SGLT-2 inhibitor, on the appearance of cardiovascular and renal events in patients with type 2 diab...
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Current guidelines for treatment of type 2 diabetes mellitus (T2DM) indicate a patient-centered approach that should go beyond glycemic control. Of the many antihyperglycemic agents available for treatment of T2DM, sodium-glucose cotransporter 2 (SGLT2) inhibitors offer the advantages of reduced glycated hemoglobin (A1C), body weight (BW), and systolic blood pressure (SBP) and are associated wi...
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BACKGROUND AND AIMS Cardiovascular disease is the most common cause of morbidity and mortality among people with type 2 diabetes mellitus (T2DM). The main contributors to cardiovascular risk in T2DM are chronic hyperglycaemia, reduced insulin sensitivity, hypertension and dyslipidaemia. Other cardiovascular risk factors include obesity and visceral adiposity, increased arterial stiffness and re...
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AIMS There is a large population of people with type 2 diabetes mellitus (T2DM) who are Muslim and fast during Ramadan. Changes in the pattern and amount of meal and fluid intake during Ramadan, in addition to the long fasting hours, may increase the risk of hypoglycaemia, hyperglycaemia, and dehydration. The Canagliflozin in Ramadan Tolerance Observational Study (CRATOS) evaluated the tolerabi...
متن کاملHealth Economic Evaluation of Canagliflozin in the Treatment of Type 2 Diabetes Mellitus in Portugal.
◾ CDM calculates indirect costs in relation to fatal events and non-fatal events. The indirect costs associated with productivity loss were included in the base case analyses and were calculated as a function of retirement age, mean salary of males and females (adjusted for employment rates), and average number of working days ◾ For T2DM and its complications, health state utilities for the mod...
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ژورنال
عنوان ژورنال: Circulation
سال: 2019
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.118.037209